TASTE EVALUATION OF SUBJECTS USING HIV PRE-EXPOSURE PROPHYLAXIS (PrEP)

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology Vol. 136; no. 1; p. e80
• Main Authors: MACEDO, Nayara Flores, de ANDRADE, Nathalia Souza, BAGGIO, Gabriela Leite, IGNÁCIO, Sérgio Aparecido, COUTO, Soraya de Azambuja Berti, SOUZA, Paulo Henrique Couto, AZEVEDO-ALANIS, Luciana Reis
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.07.2023
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2023.03.292

To evaluate the taste of the Pre-Exposure Prophylaxis (PrEP) users over a 130-day follow-up. An observational and prospective study was performed. Taste was assessed by the chemotherapy-induced taste alteration scale (CiTAS). The higher the value obtained, the greater the taste change. Subjects were evaluated before beginning the medication (T0), at the first follow-up (T1), and at the second follow-up (T2). Forty-seven participants (41 men; 6 women) were evaluated at T0. Thirty (28 men; 2 women) and 17 men were reassessed at T1 and T2, respectively. The values of the basic taste dimension (T0=1.04±0.29; T1=1.16±0.64; T2=1.11±0.48); discomfort dimension (T0=1.54±0.55; T1=1.62±0.91; T2=1.37±0.41); false taste dimension (T0=1.03±0.15; T1=1.08±0.31; T2=1.05±0.24), and final CiTAS (T0=4.78±0.86; T1=5.14±1.78, T2=4.59±0.68) indicated a worsening of taste at interval I (n=30), which refers to the days elapsed from T0 to T1, with a mean of 34.24 (±2.87; 25-108) days. Interval II (n=17) refers to the days elapsed from T1 to T2, with a mean of 99.56 (±3.68; 80-126) days. There was a worsening of the self-perception of taste after 34 days of the initial use of PrEP, and after about 100 days, it was similar to the stage before the use of medication.