A COMPENDIOUS REVIEW ON THE METABOLIC SYNDROME; ITS IMPACT ON THE QUALITY OF LIFE

• Published in: Asian journal of pharmaceutical and clinical research Vol. 11
• Main Authors: V, Rajalakshimi, M, Vijey Aanandhi
• Format: Journal Article
• Language: English
• Published: 28.12.2018
• ISSN: 0974-2441; 0974-2441
• DOI: 10.22159/ajpcr.2018.v11s4.31687

Background: Metabolic syndrome (MetS), a comprehensive condition is universally described as a group of several causative factors or abnormalities directly linked with insulin resistance that obviously augment the threat mainly for coronary heart disease, diabetes mellitus Type 2, some types of cancers and sleep disturbances, etc. MetS is a contemporary condition that covers a wide-ranging display of disorders with definite metabolic anomalies demonstrating at different times. Consequently, the threat of MetS remains epidemic. This review will potentially study significant factors such as central adiposity, insulin resistance, hypertension, and dyslipidemia; increased inflammation, environmental factors, and genetic predisposition are involved in MetS development. Purpose: This review provides the available facts to validate the relationship between MetS and quality of life. Methods: A thorough exploration in many search engines such as PubMed, Medline, Science direct, EMBASE, and Google scholar was carried out to recognize qualified studies. Results: Almost all studies suggested that MetS is significantly associated with impair quality of life. Lifestyle intervention holds the early preference and such non-pharmacological therapy combines specific suggestion on diet and physical activity with behavioral strategies. For the individuals, where contributing factors are not sufficiently condensed with lifestyle changes, pharmacological treatment should be considered. Conclusion: Therefore, the current study reviews the outline of literature interrelated with the MetS’s characterization, epidemiological existence, pathological process, and management advance for all the risk factors encompassing metabolic disorder.