THE ASSESSMENT OF MRE FINDINGS ACCORDING TO CDAI SCORE IN PATIENTS WITH CROHN’S DISEASE

• Published in: Inflammatory bowel diseases Vol. 28; no. Supplement_1; p. S22
• Main Authors: Zbroja, Monika, Kuczynska, Maryla, Cyranka, Weronika, Nowakowska, Malgorzata, Grzegorczyk, Magdalena, Siejka, Karolina, Piekarska, Monika
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 01.02.2022
• Subjects: Crohn's disease
• ISSN: 1078-0998; 1536-4844
• DOI: 10.1093/ibd/izac015.033

Abstract INTRODUCTION Crohn’s disease (CD) is a chronic inflammatory bowel disease of the gastrointestinal tract. One of the diagnostic steps is to perform a magnetic resonance enterography (MRE). The purpose of the study was to compare MRE findings with clinical index of the disease activity - CDAI score, in order to verify the usefullness of magnetic resonance enterography. SUBJECTS/METHODS The study included 46 patients who underwent MRE according to a standard protocol, with dynamic contrast-enhanced sequences. All studies were performed in prone position, using mannitol as a positive oral contrast agent. The MRE severity grading was performed according to the consensus recommendations. CDAI score was assessed prior to examination by a specialist. RESULTS 32 patients had multifocal lesions, 14 presented with unilocular lesions and 14 had a history of previous bowel resection. Penetrating disease was diagnosed in 15 subjects. The results indicate for good correlation between MRE and CDAI assessment in groups of patients with moderate and severe clinical symptoms. However, there is a significant discrepancy in MRE findings in the group of patients with mild disease activity according to CDAI. Out of 23 patients with clinically mild symptoms, 1 exhibited MRE characteristics of severe, 9 of moderate and 7 of mild inflammatory intestinal lesions. CONCLUSION There is good accordance between MRE and clinical findings in patients with prominent disease symptoms, indicating that MR enterography might be a promising modality in terms of lesion activity grading. Nonetheless, there exist a significant group of patients with mild disease symptoms, in whom MRE tends to show full spectrum of disease severity.