PULMONARY NON-HODGKIN LYMPHOMA IN A PRIMARY SJÖGREN SYNDROME PATIENT

Sjögren syndrome (SS) is a chronic autoimmune condition that mainly targets exocrine glands where it produces lymphocytic infiltrates. The clinical display varies in severity and can include malignancy association such as non-Hodgkin lymphoma. Its incidence ranges from 5 to 8%, while the risk of occ...

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Bibliographic Details
Published inRevista română de reumatologie Vol. 25; no. 2; pp. 95 - 99
Main Authors Deaconu, Claudia, Ionescu, Ruxandra, Opris, Daniela
Format Journal Article
LanguageEnglish
Published Amaltea Medical Publishing House 30.06.2016
Subjects
autoimmune disease
non-hodgkin lymphoma
sjögren syndrome
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Summary:Sjögren syndrome (SS) is a chronic autoimmune condition that mainly targets exocrine glands where it produces lymphocytic infiltrates. The clinical display varies in severity and can include malignancy association such as non-Hodgkin lymphoma. Its incidence ranges from 5 to 8%, while the risk of occurrence is 16 to 44 times higher. This article aims to describe the evolution of a patient with primary SS who developed pulmonary lymphoma for which she received Rituximab as part of the oncological therapeutic scheme. During the course of the disease she developed membranous glomerulonephritis, rarely described in these patients and low complement levels cited as predictive factor for lymphoproliferation.
ISSN:1843-0791
2069-6086
DOI:10.37897/RJR.2016.2.6