First full views of a CRISPR-guided system for gene insertion

CRISPR–Cas is a bacterial defence system that can attack invading DNA to protect host cells, or help to insert DNA safely into the genome. Structures of this latter type of CRISPR–Cas system have now been visualized. High-resolution structures of CRISPR-associated transposon system.

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Bibliographic Details
Published inNature (London) Vol. 613; no. 7945; pp. 634 - 635
Main Authors Barabas, Orsolya, Rice, Phoebe A.
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 26.01.2023
Subjects
631/337
631/535
Clustered Regularly Interspaced Short Palindromic Repeats
CRISPR-Cas Systems
Gene Editing
Humanities and Social Sciences
multidisciplinary
Mutagenesis, Insertional
News And Views
Science
Molecular biology
Structural biology
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More Information
Summary:CRISPR–Cas is a bacterial defence system that can attack invading DNA to protect host cells, or help to insert DNA safely into the genome. Structures of this latter type of CRISPR–Cas system have now been visualized. High-resolution structures of CRISPR-associated transposon system.
ISSN:0028-0836
1476-4687
DOI:10.1038/d41586-022-04584-6