PECULIARITIES OF BIOCHEMICAL INDICATOR VALUES IN PATIENTS WITH DORSOPATHY COMBINED WITH DISEASES OF THE HEPATOBILIARY SYSTEM

• Published in: Sibirskiĭ nauchnyĭ medit︠s︡inskiĭ zhurnal Vol. 38; no. 2; pp. 22 - 26
• Main Authors: Y. A. Nikolaev, E. V. Sevostyanova, V. Y. Polyakov
• Format: Journal Article
• Language: English; Russian
• Published: Russian Academy of Sciences, Siberian Branch Publishing House 01.02.2019
• Subjects: биохимические показатели; дорсопатия; заболевания гепатобилиарной системы
• ISSN: 2410-2512; 2410-2520
• DOI: 10.15372/SSMJ20180203

Aim of the study was to investigate the features of biochemical indices in patients with spinal diseases combined with diseases of the hepatobiliary system (HBS). Material and methods. The examination of 46 patients with dorsopathy combined with diseases of the hepatobiliary system has been carried out. Results and discussion. It has been shown that the transnosological polymorbidity value in patients with DP combined with diseases of HBS was statistically significant increased in comparison with groups of patients with isolated diseases (spinal diseases, HBS). It was determined that the severity of the inflammatory process, as well as disturbances of the liver functions, was higher in case of combined pathology than in the presence of isolated forms of diseases. The changes in carbohydrate, lipid and purine metabolism being the factors of severity growth of the pathology course and risk factors for the development of diabetes mellitus, atherosclerosis and associated conditions are more pronounced in case of this combined pathology. That requires a personified approach to treatment and prevention of this category of patients. The results of the study can form the basis for the development of a new medical technology for assessing the severity of condition of patients with dorsopathy combined with diseases of the hepatobiliary system.