Error evaluation of ventricular mechanics measurement in patients with discoordinate ventricular contraction [version 1; peer review: 1 approved with reservations]
In patients with discoordinate ventricular contraction, accurate identification of local mechanics from all heart regions is essential. Current measurement techniques are imperfect because a large part of the ventricular wall may be excluded, resulting in non-physiological average strain. In order t...
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Published in | F1000 research Vol. 3; p. 64 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
2014
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Subjects | |
Online Access | Get full text |
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Summary: | In patients with discoordinate ventricular contraction, accurate identification of local mechanics from all heart regions is essential. Current measurement techniques are imperfect because a large part of the ventricular wall may be excluded, resulting in non-physiological average strain. In order to evaluate this error, we propose to compare the measured average strain to a reference strain obtained by averaging through a series of measurements.
We assessed magnetic resonance (MR)-tagged images and determined circumferential strain in 160 regions of the ventricular wall in 10 patients with idiopathic dilated cardiomyopathy and left bundle branch block and 9 healthy volunteers. For each subject a global strain was calculated as the average of all measured strains. Then a reference strain was determined as the average of global strains for both experimental groups.
The reference strains of a patient group and healthy controls both had a physiological pattern, with a peak shortening of -0.034 and -0.15, respectively.
A large difference between the measured global strain and the reference strain indicates measurements which have large regions of ventricular wall which are excluded in the measurements. |
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ISSN: | 2046-1402 2046-1402 |
DOI: | 10.12688/f1000research.3612.1 |