Clinical and morphological characteristics of parathyroid carcinoma

Parathyroid carcinoma (PTC) is a rare malignant tumor with the clinical manifestation of hyperparathyroidism, reliable morphological signs of invasive growth, and poor clinical prognosis. The differential diagnosis of PTC due to the rarity of this pathology, not always explicit morphological criteri...

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Bibliographic Details
Published inArkhiv patologii Vol. 80; no. 4; p. 65
Main Authors Voronkova, I A, Mokrysheva, N G, Kazantseva, I A, Gurevich, L E
Format Journal Article
LanguageRussian
Published Russia (Federation) 2018
Subjects
parafibromin
CDC73 gene mutations
primary hyperparathyroidism
atypical adenoma
HRPT2 protein
parathyroid carcinoma
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Summary:Parathyroid carcinoma (PTC) is a rare malignant tumor with the clinical manifestation of hyperparathyroidism, reliable morphological signs of invasive growth, and poor clinical prognosis. The differential diagnosis of PTC due to the rarity of this pathology, not always explicit morphological criteria, and the lack of a certain immunohistochemical panel is complex and needs further clarification. The paper summarizes an update on the clinical and morphological characteristics of PTC.
ISSN:0004-1955
DOI:10.17116/patol201880465