Hepatoblastoma, Etiology, Case Reports

Hepatoblastoma is an uncommon malignant neoplasm in general, yet, it is the most common liver malignancy in children with the incidence about one per milion children. This type of liver tumor usually occurs before the age of three years. The etiology of hepatoblastoma remains unknown. However, there...

Full description

Saved in:
Bibliographic Details
Published inKlinická onkologie Vol. 29 Suppl 1; p. S78
Main Authors Puchmajerová, A, Křepelová, A, Indráková, J, Sítková, R, Balaščak, I, Kruseová, J, Švojgr, K, Kodet, R, Kynčl, M, Vícha, A, Macek, Jr, M
Format Journal Article
LanguageCzech
Published Czech Republic 15.01.2016
Subjects
Beckwith-Wiedemann Syndrome - complications
Child
Galactosemias - complications
Glycogen Storage Disease Type I - complications
Hepatitis B - complications
Hepatoblastoma - etiology
Hepatoblastoma - genetics
Humans
Liver Neoplasms - etiology
Liver Neoplasms - genetics
Online AccessGet more information

Cover

More Information
Summary:Hepatoblastoma is an uncommon malignant neoplasm in general, yet, it is the most common liver malignancy in children with the incidence about one per milion children. This type of liver tumor usually occurs before the age of three years. The etiology of hepatoblastoma remains unknown. However, there are some genetic conditions known to be associated with an increased risk of developing hepatoblastoma such as Beckwith-Wiedemann syndrome, hemihypertrophy, APC-associated polyposis, α-1-antitrypsin defficiency and some metabolic disorders including tyrosinemia, galactosemia and glycogen storage disease type 1. There is a higher risk of hepatoblastoma in children with very low birthweight, children who acquire hepatitis B at an early age and children with congenital biliary atresia.
ISSN:0862-495X
DOI:10.14735/amko2016S78