Characterization of the pJB12 Plasmid from Pseudomonas aeruginosa Reveals Tn 6352 , a Novel Putative Transposon Associated with Mobilization of the bla VIM-2 -Harboring In58 Integron

The -carrying In58 integron has been linked to a chromosomal location in different bacterial species, including This work reports the first fully sequenced In58-harboring plasmid, which is significantly different from the two previously identified -carrying plasmids in might have been acquired by tr...

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Bibliographic Details
Published inAntimicrobial agents and chemotherapy Vol. 61; no. 5
Main Authors Botelho, João, Grosso, Filipa, Peixe, Luísa
Format Journal Article
LanguageEnglish
Published United States 01.05.2017
Subjects
Bacterial Proteins - genetics
Base Sequence
beta-Lactamases - genetics
DNA Transposable Elements - genetics
DNA, Bacterial - genetics
Humans
Integrons - genetics
Inverted Repeat Sequences - genetics
Multilocus Sequence Typing
Plasmids - genetics
Pseudomonas aeruginosa - drug effects
Pseudomonas aeruginosa - genetics
Pseudomonas aeruginosa - isolation & purification
Pseudomonas Infections - drug therapy
Pseudomonas Infections - microbiology
RNA, Ribosomal, 16S - genetics
Sequence Analysis, DNA
transposon
Pseudomonas aeruginosa
carbapenemase
plasmid-mediated resistance
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Summary:The -carrying In58 integron has been linked to a chromosomal location in different bacterial species, including This work reports the first fully sequenced In58-harboring plasmid, which is significantly different from the two previously identified -carrying plasmids in might have been acquired by transposition of Tn , a novel transposon composed of the In58 and IS elements. The recognition of similar inverted repeat (IR) sites by IS reveals a common mobilization process associated with acquisition of the and genes.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.02532-16