Primary human herpesvirus‐6 associated with an afebrile seizure in a 3‐week‐old infant

We describe a 3‐week‐old male infant with an afebrile seizure in whom serologic and polymerase chain reaction (PCR) findings support concomitant primary human herpesvirus 6 (HHV‐6) infection. Although HHV‐6 infection has been associated with first‐time febrile seizures and encephalitis in both immun...

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Published inJournal of medical virology Vol. 66; no. 3; pp. 384 - 387
Main Authors Zerr, Danielle M., Yeung, Laurence C., Obrigewitch, Rose Mary, Huang, Meei‐Li, Frenkel, Lisa M., Corey, Lawrence
Format Journal Article
LanguageEnglish
Published New York John Wiley & Sons, Inc 01.03.2002
Wiley-Liss
Subjects
Biological and medical sciences
human herpesvirus 6
Human viral diseases
Infectious diseases
Medical sciences
Miscellaneous
PCR
seizure
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Human
Immunopathology
Encephalitis
Nervous system diseases
Herpesviridae
Epilepsy
Infant
Febrile convulsion
Immune deficiency
Cerebral disorder
Virus
Polymerase chain reaction
Herpesvirus hominis 6
Central nervous system disease
Neurological disorder
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Summary:We describe a 3‐week‐old male infant with an afebrile seizure in whom serologic and polymerase chain reaction (PCR) findings support concomitant primary human herpesvirus 6 (HHV‐6) infection. Although HHV‐6 infection has been associated with first‐time febrile seizures and encephalitis in both immunocompetent and immunocompromised hosts, it has not been associated previously with afebrile seizures in healthy infants. This report provides additional evidence of the neuropathogenic potential of HHV‐6. J. Med. Virol. 66:384‐387, 2002. © 2002 Wiley‐Liss, Inc.
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.2156