Platinum and Cobalt hydroxide – modified Platinum Electrode as Sensor for Electrochemical Oxidation of Amoxicillin

Antibiotics have recently gained in popularity due to their usage in medical treatment and the process of removing them from the environment. Amoxicillin is one of the antibiotics that constitutes the study's subject. On a Pt disc electrode and a cobalt hydroxide modified-Pt electrode, the scan...

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Bibliographic Details
Published inAlkimia: Jurnal Ilmu Kimia dan Terapan Vol. 6; no. 1; pp. 213 - 223
Main Authors Herlina, Herlina, Zulfikar, Muhammad Ali, Sirumapea, Lasmaryna, Buchari, Buchari
Format Journal Article
LanguageEnglish
Published 16.09.2022
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Summary:Antibiotics have recently gained in popularity due to their usage in medical treatment and the process of removing them from the environment. Amoxicillin is one of the antibiotics that constitutes the study's subject. On a Pt disc electrode and a cobalt hydroxide modified-Pt electrode, the scan rate and pH in the electrochemical oxidation of amoxicillin were investigated. The voltammetry measurement's current peak revealed that changing the electrode surface could increase the electrochemical response and sensitivity of the working electrodes. The Pt/Co(OH)2 modification working electrode had a high sensitivity in the electro-oxidation determination of amoxicillin, with a linear range of the sensor of 20 to 80 M and a limit of detection of 7.15 M for the Pt disc electrode and 3.64 M for the cobalt hydroxide modified Pt electrode. The findings of determination in real samples with electro-oxidation using a modified electrode were in good agreement with a confidence level of 95 percent, according to the comparing method with HPLC.
ISSN:2580-9873
2580-9881
DOI:10.19109/alkimia.v6i1.12014