Gender differences in tumor characteristics in patients with squamous cell carcinoma of the oral cavity

In the present study, records were reviewed to delineate gender differences in tumor characteristics in 256 patients with previously untreated squamous cell carcinoma of the oral cavity who had undergone surgical treatment at our Department between January 1985 and December 1977. There were 180 men...

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Bibliographic Details
Published inJapanese Journal of Oral and Maxillofacial Surgery Vol. 49; no. 10; pp. 570 - 573
Main Authors HIRATSUKA, Hiroyoshi, TSUHAKO, Wakatsu, KISHABA, Manabu, ARAKAKI, Keiichi, KANO, Takeshi, SUNAKAWA, Hajime
Format Journal Article
LanguageEnglish
Published Japanese Society of Oral and Maxillofacial Surgeons 20.10.2003
Subjects
gender differences
oral squamous cell carcinoma
tumor characteristics
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Summary:In the present study, records were reviewed to delineate gender differences in tumor characteristics in 256 patients with previously untreated squamous cell carcinoma of the oral cavity who had undergone surgical treatment at our Department between January 1985 and December 1977. There were 180 men and 76 women. As compared with tumors in men, tumors in women were characterized by, more frequent occurrence in the gum and buccal mucosa, a higher incidence of exophytic growth, earlier stages of cancer, well differentiated squamous cancer, and a lower grade of cancer invasion. The rate of disease-specific survival at 5 years in men and women were 68.8% and 92.1%, respectively. Proportional hazards models among 256 patients revealed that independent risk factors were gender and tumor stage.
ISSN:0021-5163
2186-1579
DOI:10.5794/jjoms.49.570