PO-0389 Outcome Of Very Preterm Children At School Age: Results From The Area-based Italian Action Follow-up Study

• Published in: Archives of disease in childhood Vol. 99; no. Suppl 2; pp. A372 - A373
• Main Authors: Cuttini, M, Lacchei, M, Riccio, G, Giorno, C, Rosa, C, Melon, C, Carrozzi, M, Brovedani, P, Chiandotto, V, Pessina, E, Bressan, N, Svelto, V, Voller, F
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group LTD 01.10.2014
• Subjects: Age; Cerebral Palsy; Children; Cognitive ability; Cognitive Development; Followup Studies; Gestational age; Infants; Mental development; Paralysis; Pregnancy; Sensorimotor system
• ISSN: 0003-9888; 1468-2044
• DOI: 10.1136/archdischild-2014-307384.1035

Background and aimsChildren born before 32 weeks of gestational age (GA) have increased risk of neurological, sensory, cognitive and behavioural problems. The latter become evident at school age, but follow-up is rarely continued up to this time. We present preliminary results of ongoing follow-up at school age of the Italian ACTION area-based cohort.MethodsAll infants born <32 weeks GA in 2003–2004 in three regions (Lazio, Tuscany and Friuli Venezia-Giulia) and survived to school-age were invited. The Kaufman Assessment Battery second edition (KABC-II) and selected items of NEPSY-II were used to assess cognitive and neuropsychological development. Only results for Lazio and Trieste area in FVG, where follow-up is already completed, are included (n 390, response rate 58%).ResultsFifty-six percent of children (n 218) were males; 35% (1379 were ≤28 weeks GA. About 8% (n 30) had cerebral palsy; six children (1.5%) were blind or almost blind, and 12 (3.1%) required hearing aids. Twenty-two percent of children had KABC-II Mental Development Index (MPI) below average (29.9% in children born ≤28 weeks gestation, p = 0.008). Lower MPI scores were associated with impaired neuropsychological abilities.ConclusionsWhile most children have cognitive level within normal range, lower KABC-II and NEPSY-II scores were found particularly in the more preterm group. Sensorimotor abilities were the most frequently compromised neuropsychological functions.AcknowledgementsThe ACTION follow-up project was funded by the Italian Ministry of Health and by the Chiesi Farmaceutici S.p. A.