Traumatic neuroma of the right posterior hepatic duct with an anatomic variation masquerading as malignancy: a case report

• Published in: Kosin Medical Journal (Online) Vol. 38; no. 1; pp. 66 - 71
• Main Authors: Shim, Jae Ryong, Lee, Tae Beom, Choi, Byung Hyun, Ryu, Je Ho, Lee, Jung Hee, Yang, Kwangho
• Format: Journal Article
• Language: English
• Published: Kosin University College of Medicine 31.03.2023
• Subjects: case reports; cholangiocarcinoma; neuroma
• ISSN: 2005-9531; 2586-7024
• DOI: 10.7180/kmj.22.135

Traumatic neuroma (TN), also known as amputation neuroma, is a reactive hyperplasia of nerve fibers and connective tissue arising from Schwann cells after trauma or surgery. TN of the bile duct is usually asymptomatic, but rarely can lead to right upper quadrant pain, biliary obstruction, and acute cholangitis. It is very difficult to discriminate TN from malignancy before surgery, although doing so could avoid an unnecessary radical resection of the lesion. In the course of surgery, TN can be caused by unintentional injury of a nerve fiber near the common bile duct (CBD) and heat damage to an artery, complete ligation of an artery, and excessive manipulation of the CBD. Therefore, to prevent TN after cholecystectomy, surgery should be performed carefully with appropriate consideration of anatomic variations, and a cystic duct should not be resected too close to the CBD. The possibility of TN should be considered if a patient who has undergone CBD resection with hepaticojejunostomy or cholecystectomy long ago experiences symptoms of jaundice, cholangitis, or obliteration of the CBD. In this report, we present a case of TN mimicking cholangiocarcinoma that emerged from a cystic duct stump after cholecystectomy.