PO-0857 Central Nervous Thrombophlebitis And BehÇet Disease

• Published in: Archives of disease in childhood Vol. 99; no. Suppl 2; p. A532
• Main Authors: Boutrid, N, Rahmoune, H, Rahmoune, FC, Loucif, A, Bioud, B
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group LTD 01.10.2014
• Subjects: Anticoagulants; Aphthous stomatitis; Cerebral blood flow; Colchicine; Headache; Ischemia; Magnetic resonance imaging; Nausea; Steroid hormones; Steroids; Stomatitis; Superior sagittal sinus; Thromboembolism; Thrombophlebitis; Thrombosis; Ulcers; Uveitis; Vein & artery diseases
• ISSN: 0003-9888; 1468-2044
• DOI: 10.1136/archdischild-2014-307384.1483

IntroductionBehcet’s Disease (BD) is manifested by a triad of relapsing hypopyon uveitis, aphthous stomatitis and genital ulcers.We present the case of a school-aged boy with a Behçet-related acute cerebral venous thrombosis.Material and methodA 8 years old boy is admitted for acute and severe headaches with nausea.Clinical examination notes a febrile child with marked aphtous mouth (with a history of genital ‘burns’).ESR and CRP are mildly high, while cerebral angio-CT reveals a superior sagittal sinus occlusion.Steroids and palliative management completely resolve these symptoms, while angio-MRI confirms the isolated thrombophlebitis.DiscussionThe major manifestations of vascular Behcet Disease include venous occlusion, arterial occlusion and aneurysm formation.Cerebral venous thrombosis (CVT) results in signs and symptoms of increased intracranial pressure, like for our child.Steroids remain the mainstay initial treatment, with a particular attention to anticoagulation and adjunction/relay with colchicine.ConclusionCerebral venous thrombosis may reveal BD is associated with a good prognosis when treated promptly, specially in paediatric patients.