Vaccination as a protective factor for medical workers during the COVID-19 pandemic

• Published in: Science and Innovations in Medicine Vol. 9; no. 1; pp. 37 - 43
• Main Authors: Medvedeva, Evgeniya А., Maryin, German G., Svitich, Oksana A., Kaira, Alla N., Zykov, Kirill A., Ploskireva, Antonina A., Nazarov, Dmytrii A., Volynkov, Igor О., Kuzin, Aleksandr A., Zobov, Andrei Е., Romanova, Kseniya G.
• Format: Journal Article
• Language: English
• Published: Samara State Medical University 06.05.2024
• Subjects: coronavirus; risks; vaccination
• ISSN: 2500-1388; 2618-754X
• DOI: 10.35693/SMI568092

Aim – to evaluate the effectiveness of vaccination when using various vaccines against COVID-19 approved for use in Russia among medical staff and faculty of medical higher educational institutions according to online questionnaires. Material and methods. A cross-sectional study was conducted online from January to March 2022 (circulation period of the omicron genovariant). The survey was completed by 6032 respondents, 2114 respondents were excluded from the study. The remaining 3918 respondents were included in the the analysis. Results. 47 (0.1%) medical workers reported COVID-19 incidence within 21 days after the second dose of the vaccine. 616 (16.8%) medical workers reported COVID-19 incidence within 5 months after two vaccinations. 116 (46.4%) unvaccinated respondents reported a laboratory-confirmed new coronavirus infection within 5 months prior to the survey. Lack of vaccination increased the risk of SARS-CoV-2, OR 1.78 ± 0.14 (95% CI 1.34-2.36). It was found that gender and age were not a risk factor for the onset of the disease in the post-vaccination period. The presence of SARS-CoV-2 in medical history increased the risk of developing the disease in the post-vaccination period. Conclusion. The analysis revealed that vaccination had significantly higher protection effect for 1.5 months after vaccination and significantly reduced in 5 months after vaccination.