Haemophagocytic lymphohistiocytosis post-ChAdOx1 nCoV-19 vaccine: A rare case

The severe acute respiratory syndrome coronavirus 2 pandemic started in December 2019, spread like wildfire and took an immense toll on human life. ChAdOx1 nCoV-19 vaccine was used worldwide for the prevention of Covid-19. Covid-19 has been implicated in the causation of severe haemophagocytic lymph...

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Published inThe National medical journal of India Vol. 37; no. 2; pp. 90 - 92
Main Authors Marwah, Vikas, Choudhary, Robin, Kumar, Tentu Ajai, Sharma, Manish
Format Journal Article
LanguageEnglish
Published India 01.03.2024
Subjects
Adult
ChAdOx1 nCoV-19 - adverse effects
COVID-19 - complications
COVID-19 - prevention & control
COVID-19 Vaccines - adverse effects
Humans
Lymphohistiocytosis, Hemophagocytic - diagnosis
Lymphohistiocytosis, Hemophagocytic - etiology
Male
SARS-CoV-2 - immunology
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Summary:The severe acute respiratory syndrome coronavirus 2 pandemic started in December 2019, spread like wildfire and took an immense toll on human life. ChAdOx1 nCoV-19 vaccine was used worldwide for the prevention of Covid-19. Covid-19 has been implicated in the causation of severe haemophagocytic lymphohistiocytosis (HLH) syndrome. However, the same has not been reported with ChAdOx1 nCoV-19 vaccine in the literature. We report a young man who developed secondary HLH post-ChAdOx1 nCoV-19 vaccination.
Bibliography:ObjectType-Case Study-2
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ISSN:0970-258X
2583-150X
2583-150X
DOI:10.25259/NMJI_MS_466_21