Case Report: Splenectomy in Sickle Cell Anemia: Report of a Case and Review of the Literature

Abstract 1. A case of sickle cell anemia who had numerous hemolytic crises and also hypersplenic effects such as pancytopenia was treated by splenectomy with marked improvement in general condition and in the blood. The literature relating to this subject is reviewed. Those cases with the largest sp...

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Bibliographic Details
Published inBlood Vol. 6; no. 4; pp. 365 - 371
Main Authors SHOTTON, DONALD, CROCKETT, CHARLES L., LEAVELL, BYRD S.
Format Journal Article
LanguageEnglish
Published 01.04.1951
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Summary:Abstract 1. A case of sickle cell anemia who had numerous hemolytic crises and also hypersplenic effects such as pancytopenia was treated by splenectomy with marked improvement in general condition and in the blood. The literature relating to this subject is reviewed. Those cases with the largest spleens appear to have shown the most striking degrees of improvement. 2. In cases of sickle cell anemia showing various indications of hypersplenism, and excessive hemolysis, splenectomy may be a rational therapeutic procedure.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V6.4.365.365