A pilot, exploratory study to demonstrate the efficacy of a novel adjuvant herbal liquid supplement for skin rejuvenation and anti-aging

• Published in: International Journal of Research in Dermatology Vol. 7; no. 6; p. 792
• Main Authors: Janaki, C. S., Sachdev, Mukta, R., Ritambhara K.
• Format: Journal Article
• Language: English
• Published: 27.10.2021
• ISSN: 2455-4529; 2455-4529
• DOI: 10.18203/issn.2455-4529.IntJResDermatol20214203

Background: Aging of skin has both intrinsic and extrinsic causative factors. Impact of oral consumption of a novel multi-component herbal skin water supplement (HSWS) by Diabliss was investigated in a pilot exploratory study. Methods: A 90-day open label clinical study among 40 healthy male and female subjects aged 35-50 years, presenting with signs of aging including wrinkles and pigmentation related skin concerns. The study assessments included dermatological, instrumental and imaging evaluation to investigate the impact of the Diabliss HSWS in providing improvements in various signs of aging. Results: The Diabliss HSWS was able to show significant improvement in skin elasticity parameters by Cutometer® with improvements that ranged between 23-54% for the six elasticity parameters, skin hydration improvements as measured by Corneometer® in forehead (30%) and cheek (34%), wrinkles reduction reductions by Antera® in forehead (25%) and crows feet area (20%), texture improvements in forehead (25%) and crows feet area (20%), reduction L* value on the localized pigmentation/ spot of 6%. The subject assessments also reported improvement in the skin and general health. There were no product related AE/SAE and the product was found to be safe and well tolerated. Conclusions: In conclusion, this water based oral nutraceutical is a novel delivery system for a skin rejuvenation adjuvant therapy which is cosmetically and systemically acceptable and tolerable for patients.