S1304 Efficacy and Safety of Gastric Peroral Endoscopic Myotomy for Refractory Gastroparesis

• Published in: The American journal of gastroenterology Vol. 118; no. 10S; pp. S994 - S995
• Main Authors: Yousaf, Muhammad Nadeem, Fard, Darian, Deda, Xheni, Gangu, Karthik, Ghady, Moafa, Basida, Sanket, Malik, Alexander K., Gandhi, Mustafa, Swi, Ahmed I.A., Shah, Niraj, Hammoud, Ghassan M.
• Format: Journal Article
• Language: English
• Published: New York Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins 01.10.2023
• Subjects: Abdomen; Diabetes; Endoscopy; Length of stay; Patients; Scleroderma; Success
• ISSN: 0002-9270; 1572-0241
• DOI: 10.14309/01.ajg.0000954856.54946.d9

The mean procedure time was 80±24 min and the mean length of hospital stay was 1.0 day. After G-POEM, there was a significant reduction in mean emergency room visits due to gastroparesis-related symptoms (1.6±3.3 vs 0.2±0.8 (P< 0.03)). Baseline characteristics, procedure outcomes and adverse events Baseline characteristics of patients who underwent G-POEM % (n)* Age (years) 58.5 ± 14.7 Sex  Female 72% (18)  Male 28% (7) Race  White 100% (25)  Weight (kg) 87.4 ± 28.4  BMI (Kg/m2) 31.3 ± 8.5  Smoking 24% (6) Etiologies of gastroparesis  Idiopathic 36% (9)  Diabetes 36% (9)  Post-Surgical 20% (5)  Scleroderma 4% (1)  Marijuana 4% (1)  Duration of symptoms 41.0 ± 50.6  Duration of follow-up (months) 7.6 +6.1 Procedure outcomes  Technical success 100% (25)  Clinical success (GCSI improvement >25%) 88% (22)  Need for reintervention 12% (3)  Mean procedure time(mins) 80 + 24.77  Mean length of hospital stay (days) 1.0 Before G-POEM After G-POEM P-value GCSI score 32.8 ± 6.8 12.0 ± 7.9 < 0.001 Food retention on GES 47.2 ± 27.0 43.4 ± 35.0 0.3 Mean Hospitalization (days) 1.6 ± 3.4 0.2 ± 0.8 0.03 Adverse events Peri-procedure adverse events Post-procedure adverse events Bleeding 1 (4%) Abdominal pain 6 (24%) Serosal injury 1 (4%) Nausea + abdominal pain 5 (20%) Perforation 0 (0%) Wound infection 0 (0%) Mild adverse events 2 (8%) Aspiration pneumonia 0 (0%) Severe adverse events 0 (0%) Stenosis 0 (0%) *Values mean ± SD for continuous variables and n (column %) for categorical variables.