Clinical case of Bloch — Sulzberger syndrome

Purpose.To present a clinical case of Bloch Sulzberger syndrome. Material and methods. The examinations were performed to diagnose the disease: а visual examination of the skin, cytological analysis of the gallbladder fluid, general and biochemical blood tests, genetic research. Results.During a vis...

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Published inVestnik dermatologij i venerologij Vol. 96; no. 3; pp. 63 - 67
Main Authors Krasnova, Nadezhda V., Chernova, Tatyana A., Alekseeva, Irina V., Gimalieva, Geliya G., Misyakova, Tatiana, Sinitsyna, Larisa G.
Format Journal Article
LanguageEnglish
Published State Scientific Center of Dermatovenereology and Cosmetology 29.09.2020
Subjects
bloch — sulzberger syndrome
verrucous rashes
vesiculo-bullous
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Summary:Purpose.To present a clinical case of Bloch Sulzberger syndrome. Material and methods. The examinations were performed to diagnose the disease: а visual examination of the skin, cytological analysis of the gallbladder fluid, general and biochemical blood tests, genetic research. Results.During a visual examination of the skin, a differential diagnosis was made with infectious dermatitis, toxic-allergic dermatitis, epidermolysis bullosa and linear IgA-dependent dermatosis in children. Crucial in the diagnosis belonged to a genetic study, after which a deletion of exons 410 of the IKBKG gene was detected, which confirmed Bloch Sulzberger syndrome. Conclusion.Newborns with vesicle-bullous rashes entering the neonatal pathology department and observed by neonatologists require a thorough examination, a mandatory consultation of a dermatologist inorder to determine further management tactics.
ISSN:0042-4609
2313-6294
DOI:10.25208/vdv1117