S3674 A Rare Case of Idiosyncratic Metronidazole-Induced Severe Liver Injury

Most frequently reported adverse effects include nausea, metallic taste and diarrhea. Viral hepatitis and autoantibody testing was negative. Metronidazole is primarily metabolized by the liver, and overdose has been reported to cause hepatotoxicity. Additionally, this case highlights the importance...

Full description

Saved in:
Bibliographic Details
Published inThe American journal of gastroenterology Vol. 118; no. 10S; pp. S2380 - S2381
Main Authors Narang, Natasha, Gutierrez, Victor Arce, Gomez, Paul, Nevah Rubin, Moises I.
Format Journal Article
LanguageEnglish
Published New York Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins 01.10.2023
Subjects
Biopsy
Enzymes
Hepatitis
Liver
Phosphatase
Online AccessGet full text

Cover

More Information
Summary:Most frequently reported adverse effects include nausea, metallic taste and diarrhea. Viral hepatitis and autoantibody testing was negative. Metronidazole is primarily metabolized by the liver, and overdose has been reported to cause hepatotoxicity. Additionally, this case highlights the importance of thorough investigation of all recently taken medications in a patient presenting with acute liver injury, and high index of suspicion for agents that may not otherwise be established as hepatotoxic (Table 1).Table 1.
ISSN:0002-9270
1572-0241
DOI:10.14309/01.ajg.0000964336.59429.36