Cofilin Activation during Ca2+-Triggered Secretion from Adrenal Chromaffin Cells

• Published in: Biochemical and biophysical research communications Vol. 286; no. 3; pp. 493 - 498
• Main Authors: Birkenfeld, Jörg, Kartmann, Bettina, Betz, Heinrich, Roth, Dagmar
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 24.08.2001
• Subjects: actin; catecholamine secretion; Lim kinase; actin; Lim kinase; catecholamine secretion

Cofilin is one of the major actin depolymerizing proteins in eukaryotic cells and involved in many membrane modulating activities, such as cell growth and motility. Here we examined whether cofilin is activated upon Ca2+ regulated noradrenalin secretion from bovine adrenal chromaffin cells. We found...