Isocitrate lyase isozymes and their role in organisms with different levels of organization

The current state of the problem regarding the prevalence of isocitrate lyase isoenzymes is discussed. Isocitrate lyase is an essential enzyme of the glyoxylate cycle, which is widespread in nature and functions in different physiological periods of life in many organisms. To date, there has been no...

Full description

Saved in:
Bibliographic Details
Published inBiology bulletin reviews Vol. 4; no. 4; pp. 323 - 334
Main Authors Eprintsev, A. T., Salnikov, A. V., Haba, A. M., Zaichikova, M. V.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.07.2014
Subjects
Biochemistry
Biomedical and Life Sciences
Cell Biology
Ecology
Life Sciences
Zoology
isocitrate lyase
glyoxylate cycle
expression
isoenzymes
gluconeogenesis
Online AccessGet full text

Cover

More Information
Summary:The current state of the problem regarding the prevalence of isocitrate lyase isoenzymes is discussed. Isocitrate lyase is an essential enzyme of the glyoxylate cycle, which is widespread in nature and functions in different physiological periods of life in many organisms. To date, there has been no consensus regarding the induction of this isozyme in animals and bird tissues, despite numerous studies into the functioning of isocitrate lyase isozymes in cells of bacteria, protists, fungi, plants, and nematodes. The kinetic and physical-chemical parameters of plant and animal isocitrate lyases and the molecular-biological aspects of their operation, as well as mechanisms for the expression regulation of these enzymes, are considered. The physiological role of isocitrate lyase isoenzymes in organisms of different taxonomic groups is discussed.
ISSN:2079-0864
2079-0872
DOI:10.1134/S2079086414040021