Mapping of the Human Ribosomal Large Subunit Protein GeneRPL29to Human Chromosome 3q29–qter

• Published in: Genomics (San Diego, Calif.) Vol. 46; no. 1; pp. 148 - 151
• Main Authors: Garcia-Barcelo, M., Law, P.T.W., Tsui, S.K.W., Fung, K.P., Lee, C.Y., Waye, M.M.Y.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 15.11.1997
• ISSN: 0888-7543; 1089-8646
• DOI: 10.1006/geno.1997.4990

The human ribosomal protein L29, which we reported previously, was subsequently shown to have the same nucleotide sequence as that of cell surface heparin/heparan sulfate-binding protein, designated HP/HS interacting protein. A polymerase chain reaction-based strategy was used to distinguish the functional intron-containing geneRPL29(HGMW-approved symbol) from multiple pseudogenes. By somatic cell hybrid analysis, radiation hybrid mapping, and fluorescencein situhybridization, we have locatedRPL29on the telomeric region of the q arm of chromosome 3.RPL29is the most distal marker of the long arm of chromosome 3. Of the human ribosomal protein genes mapped,RPL29is the shortest distance from another ribosomal protein gene marker,RPL35awhich has also been mapped to the 3q29–qter region.