Comparison of the efficacy of microneedling versus CO 2 fractional laser to treat striae alba: A randomized clinical trial

Striae distensae (SD) are common skin conditions that have posed a significant challenge regarding their assessment and treatment. The present study aimed to evaluate the efficacy of microneedling in comparison to fractional CO laser therapy. Similar striae were selected and photographed. Each side...

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Bibliographic Details
Published inDermatologic therapy Vol. 35; no. 1; p. e15212
Main Authors Saki, Nasrin, Rahimi, Farzaneh, Pezeshkian, Fatemeh Sadat, Parvar, Seyedeh Yasamin
Format Journal Article
LanguageEnglish
Published United States 01.01.2022
Subjects
Adult
Carbon Dioxide
Dry Needling - methods
Humans
Lasers, Gas - therapeutic use
Patient Satisfaction
Striae Distensae - therapy
Treatment Outcome
clinical trial
stretch marks
striae distensae
fractional CO2 laser
microneedling
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Summary:Striae distensae (SD) are common skin conditions that have posed a significant challenge regarding their assessment and treatment. The present study aimed to evaluate the efficacy of microneedling in comparison to fractional CO laser therapy. Similar striae were selected and photographed. Each side was randomly assigned to be treated with CO fractional laser or microneedling four times at monthly intervals and followed up for 10 months. Outcome measures including the length and width of the largest striae, dermatologist assessed improvement, patients' satisfaction, and visual analog scale (VAS) were assessed. Wilcoxon signed-rank test and Mann-Whitney U test were used to assess the efficacy of treatments. Forty patients with a mean age of 28.1 years were included. The median cross-section of the largest striae decreased significantly in both groups (P-value <0.001), without statistically significant differences between the two groups before and 6 months after treatment. VAS also improved significantly in both groups, and there were no statistically significant differences between the two treatments in all visits. No clinically significant adverse effects were observed. Fractional CO laser and microneedling are both efficient treatments to resolve SD. A new light should be shed on the microneedling modality as it is more economical than the other treatment options.
ISSN:1396-0296
1529-8019
DOI:10.1111/dth.15212