Review of Diagnostic Challenges and Literature Data in Paraneoplastic Limbic Encephalitis: A Case Presentation

• Published in: Ars medica tomitana Vol. 30; no. 3; pp. 72 - 76
• Main Authors: Codreanu-Balaban, Ramona Andreea, Stuparu, Alina Zorina, Musat, Daniela, Baz, Radu-Andrei, Baz, Radu, Docu-Axelerad, Silviu, Vranau, Diana-Marina, Tase, Cristina Ramona, Gogu, Anca Elena, Jianu, Dragos Catalin, Frecus, Corina Elena, Muja, Lavinia-Florenta, Tony, Hangan Laurentiu, Axelerad, Any
• Format: Journal Article
• Language: English
• Published: Sciendo 01.08.2024
• Subjects: autoimmune disease; cerebrospinal fluid; limbic encephalitis; prognosis; small-cell lung cancer
• ISSN: 1841-4036; 1841-4036
• DOI: 10.2478/arsm-2024-0011

Paraneoplastic limbic encephalitis is a rare condition reported in practice. It is most commonly associated with small cell lung cancer (SCLC). This case report is offered to aid physicians in making informed decisions about timing and type of treatment and is evident, that quick diagnosis is critical for both, neurologists and oncologists. The presentation reviews the case of a female patient diagnosed with limbic encephalitis. Further research is needed to establish clinical, laboratory and instrumental criteria that may be related to outcomes. The purpose of this paper is to present the potential repercussions of a delayed diagnosis and highlight the beneficial results of specific investigations and symptomatic therapy. Comprehensive familiarity with clinical presentations and the limitations of current diagnostic procedures is imperative for neurologists. Equally essential is this understanding for radiologists, serving as the basis for accurate diagnostic analyses derived from imaging findings. The intricate nature of neurological disorders sometimes necessitates the cooperation of neurologists, radiologists, and, in this particular instance, oncologists, in order to achieve precise diagnosis and develop successful treatment approaches.