FONTAN PHENOTYPES HAVE SIGNATURE BIOMARKER EXPRESSION PROFILES

Methods 35 clinically stable Fontan patients (68.5% female, mean age 31.6 +/- 9.0 yrs, 65.7% systemic left ventricle) were characterized based on echo parameters as having cardiac phenotype (systolic or diastolic dysfunction), non-cardiac phenotype (normal ventricle with low systemic vascular resist...

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Published inJournal of the American College of Cardiology Vol. 71; no. 11; p. A627
Main Authors Saraf, Anita, De Stearcke, Christine, Gerardin, Jennifer, Pernetz, Maria, Ephrem, Georges, Adjei, Stacey, Jennings, Staci, Abdelhadi, Naser, Kim, Jonathan, Rodriguez, Fred, Book, Wendy
Format Journal Article
LanguageEnglish
Published New York Elsevier Inc 10.03.2018
Elsevier Limited
Subjects
Biomarkers
Cardiology
Heart surgery
Phenotypes
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Summary:Methods 35 clinically stable Fontan patients (68.5% female, mean age 31.6 +/- 9.0 yrs, 65.7% systemic left ventricle) were characterized based on echo parameters as having cardiac phenotype (systolic or diastolic dysfunction), non-cardiac phenotype (normal ventricle with low systemic vascular resistance)) or mixed phenotype. Differences in biomarker expression was evaluated by comparing mean values using ANOVA, and students T-test Results Patient characteristics are noted in Table 1.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(18)31168-9