Choice of reference region for the normalization of brain Cerebral Blood Volume maps in comparative studies

Introduction Perfusion MR imaging of Cerebral Blood Volume (CBV) maps is a promising alternative to nuclear medicine imaging for the evaluation and early detection of patients with dementia. For the comparative analysis of CBV maps, the large physiological variability between subjects recommends a n...

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Published inNeuroImage (Orlando, Fla.) Vol. 47; p. S125
Main Authors Reig, S, de Villoria, J Guzmán, Olazarán, J, LaCalle, M, Martino, E, Mateos, JM, Cruz, I, García, V, Desco, M
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier Inc 01.07.2009
Elsevier Limited
Subjects
Comparative analysis
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Summary:Introduction Perfusion MR imaging of Cerebral Blood Volume (CBV) maps is a promising alternative to nuclear medicine imaging for the evaluation and early detection of patients with dementia. For the comparative analysis of CBV maps, the large physiological variability between subjects recommends a normalization step prior to the quantitative analysis.
ISSN:1053-8119
1095-9572
DOI:10.1016/S1053-8119(09)71197-8