Front Cover: Relevance of Palladium to Radiopharmaceutical Development Considering Enhanced Coordination Properties of TE1PA (Chem. Eur. J. 41/2022)

The coordination chemistry of palladium is poorly developed in nuclear medicine due to the lack of appropriate ligands capable of fulfilling all the criteria required for an in vivo application. By showing that the monopicolinate cyclam TE1PA is a highly relevant chelator for natural and radioactive...

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Published inChemistry : a European journal Vol. 28; no. 41
Main Authors Pineau, Julie, Lima, Luís M. P., Platas‐Iglesias, Carlos, Zeevaart, Jan Rijn, Driver, Cathryn H. S., Le Bris, Nathalie, Tripier, Raphaël
Format Journal Article
LanguageEnglish
Published 20.07.2022
Subjects
complexation
cyclam
cyclam monopicolinate
palladium(II)
palladium-109
radiolabeling
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Summary:The coordination chemistry of palladium is poorly developed in nuclear medicine due to the lack of appropriate ligands capable of fulfilling all the criteria required for an in vivo application. By showing that the monopicolinate cyclam TE1PA is a highly relevant chelator for natural and radioactive Pd, we have opened avenues to enrich the area of palladium‐based targeted radiotherapies. This cover represents the early stage of their expansion. More information can be found in the Research Article by C. H. S. Driver, N. Le Bris, R. Tripier, and co‐workers (DOI: 10.1002/chem.202200942).
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.202201839