Psoriatic Arthritis: A comprehensive review for the dermatologist Part I: Epidemiology, Comorbidities, Pathogenesis, and Diagnosis

Psoriatic arthritis (PsA) is an inflammatory seronegative arthritis strongly associated with psoriasis. Recognition of the clinical features of PsA is critical, as delayed detection and untreated disease may result in irreparable joint damage, impaired physical function, and a significantly reduced...

Full description

Saved in:
Bibliographic Details
Published inJournal of the American Academy of Dermatology
Main Authors Perez-Chada, Lourdes M., Elman, Scott, Villa-Ruiz, Camila, Armstrong, April W., Gottlieb, Alice B., Merola, Joseph F.
Format Journal Article
LanguageEnglish
Published Elsevier Inc 08.06.2024
Subjects
Psoriasis
psoriatic arthritis
GWASs
PGE2
IL
CASPAR
Psoriasis
CI
IBD
Glu45
DIP
TYK2
TNF
RA
NF-κB
RRR
Th
PIP
psoriatic arthritis
HLA
JAK2
PsA
BMI
Online AccessGet full text

Cover

More Information
Summary:Psoriatic arthritis (PsA) is an inflammatory seronegative arthritis strongly associated with psoriasis. Recognition of the clinical features of PsA is critical, as delayed detection and untreated disease may result in irreparable joint damage, impaired physical function, and a significantly reduced quality of life. Dermatologists are poised for the early detection of PsA, as psoriasis predates its development in as many as 80% of patients. In an effort to further acquaint dermatologists with PsA, this review provides a detailed overview, emphasizing its epidemiology, comorbidities, etiopathogenesis, and diagnostic features.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2024.03.058