Front Cover Picture: Asymmetric Bioreduction of β‐Activated Vinylphosphonate Derivatives Using Ene‐Reductases (Adv. Synth. Catal. 23/2017)

The front cover image, provided by Piotr Kiełbasiński, Mélanie Hall and collaborators, illustrates the stereoselective bioreduction of activated vinylphosphonates catalyzed by Old Yellow Enzyme homologues, which can be easily produced through recombinant expression in E. coli cells. This stereocompl...

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Bibliographic Details
Published inAdvanced synthesis & catalysis Vol. 359; no. 23; p. 4067
Main Authors Janicki, Ignacy, Kiełbasiński, Piotr, Turrini, Nikolaus G., Faber, Kurt, Hall, Mélanie
Format Journal Article
LanguageEnglish
Published 11.12.2017
Subjects
asymmetric catalysis
biocatalysis
chiral phosphonates
ene-reductases
enzymes
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Summary:The front cover image, provided by Piotr Kiełbasiński, Mélanie Hall and collaborators, illustrates the stereoselective bioreduction of activated vinylphosphonates catalyzed by Old Yellow Enzyme homologues, which can be easily produced through recombinant expression in E. coli cells. This stereocomplementary method to current asymmetric hydrogenation protocols provides access to α‐chiral phosphonates of high enantiomeric purity. (Picture from E. coli bacteria – NIAID; Under Creative Common license BY‐SA). Details can be found in the full paper on pages 4190–4196 (I. Janicki, P. Kiełbasiński, N. G. Turrini, K. Faber, M. Hall, Adv. Synth. Catal. 2017, 359, 4190–4196; DOI: 10.1002/adsc.201700716).
ISSN:1615-4150
1615-4169
DOI:10.1002/adsc.201701440