Inhibitory effects of a liquid dispersion of fluoroaluminosilicate glass on the attachment of dental plaque to the dental root surface

• Published in: Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) Vol. 56; no. 1; pp. 25 - 31
• Main Authors: Kurose, Shintaro, Shirakawa, Satoshi, Miyazaki, Ayako, Suzuki, Takuma, Tikenji, Akiyosi, Yashima, Akihiro, Gomi, Kazuhiro
• Format: Journal Article
• Language: English; Japanese
• Published: JAPANESE SOCIETY OF PERIODONTOLOGY 11.04.2014
• Subjects: NanoSeal; plaque adhesion; root caries; root exposure
• ISSN: 0385-0110; 1880-408X
• DOI: 10.2329/perio.56.25

The formation of plaque to exposed tooth root surfaces, which leads to periodontitis and root caries,is a major obstacle in the management of patients with periodontal disease. NanoSeal®, a commercially available liquid formulation of fluoroaluminosilicate glass that is used as a hypersensitivity suppressor, has also been demonstrated to improve the acid resistance of root surfaces. We hypothesized that the use of this substance might also suppress plaque deposition on the root surface by changing the charge of the surface. The aim of this study was to investigate the effect of applying NanoSeal® to the dentin surface in preventing the formation of plaques. We cultured S. mutans on bovine dentin pieces for 48 hours and then observed the biofilm formation on the pieces under a scanning electron microscope after rinsing. Furthermore, we applied NanoSeal® to the teeth of patients (10 patients) with anterior tooth root exposure and evaluated the plaque adhesion status on the root surfaces after 2 and 4 weeks in a randomized double-blind test. Formation of a clear biofilm was observed in the uncoated group, but only scattered bacteria were detected in the NanoSeal®-coated group. The plaque adhesion rate was lower in the NanoSeal®-coated group, although the difference was not significant. In the in vitro study, the inhibitory effect of NanoSeal® on the biofilm adhesion was assessed after rinsing the dentin pieces with water ; the results revealed that the strength of adhesion of the biofilm to the tooth surface had likely decreased. We plan to carry out a clinical study in the future to examine plaque adhesion to the tooth surface. Nihon Shishubyo Gakkai Kaishi (J Jpn Soc Periodontol) 56(1)：25-31, 2014.