Essential oils used in Modified Drug Delivery and its formulation of Liposomes for Topical Purpose
The aim of the article is to provide the current and recent years knowledge about the application of the targeted marketing efforts and they have advantages over the medicine and fulfill with a nutritive value which nourishes the skin cells and protects from UV rays, loss of moisture. [...]essential...
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Published in | Research journal of pharmacology and pharmacodynamics Vol. 12; no. 1; pp. 34 - 38 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Raipur
A&V Publications
2020
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Subjects | |
Online Access | Get full text |
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Summary: | The aim of the article is to provide the current and recent years knowledge about the application of the targeted marketing efforts and they have advantages over the medicine and fulfill with a nutritive value which nourishes the skin cells and protects from UV rays, loss of moisture. [...]essential oil is widely used and paid more attention to pharmaceutical industries [5]. Advantage of Liposomes [20, 21]: * Liposomes are biocompatible, completely biodegradable, non-toxic and non-immunogenic. * Suitable for delivery of hydrophobic, amphipathic and hydrophilic drugs. * Protect the encapsulated drug from the external environment. * Reduction toxicity and increased stability- As the therapeutic activity of chemotherapeutic agents can be improved through liposome encapsulation. * Reduce exposure of sensitivity tissues to toxic drugs. 1.2. Essential oils loaded liposomes in different ratios [22]: * EO and phospholipid ratio (1:2.7 w/w and 1:1.5 w/w) * Phosphatidylcholine, cholesterol and EO (39:5.2:9mg/mL) 1.3.Formulation of EO loaded liposomal Cream [28, 29]: The oily phase and aqueous phase were heated up to 70°C and mixed using homogenizer by addition of preservative and fragrance with constant mixing until mixture cools. 2. |
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ISSN: | 0975-4407 2321-5836 |
DOI: | 10.5958/2321-5836.2020.00008.7 |