Potent, selective 3-pyridylethanolamine β3 adrenergic receptor agonists possessing a thiazole benzenesulfonamide pharmacophore

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Bibliographic Details
Published inBioorganic & medicinal chemistry letters Vol. 10; no. 17; pp. 1971 - 1973
Main Authors MATHVINK, R. J, TOLMAN, J. S, MACINTYRE, D. E, TOTA, L, WYVRATT, M. J, FISHER, M. H, WEBER, A. E, CHITTY, D, CANDELORE, M. R, CASCIERI, M. A, COLWELL, L. F, LIPING DENG, FEENEY, W. P, FORREST, M. J, HOM, G. J
Format Journal Article
LanguageEnglish
Published Oxford Elsevier 01.09.2000
Subjects
Biological and medical sciences
Catecholaminergic system
Medical sciences
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology. Drug treatments
Fissipedia
Sulfur nitrogen heterocycle
Carnivora
Agonist
Aminoalcohol
Sulfonamide
Nitrogen heterocycle
Thiazole derivatives
Oral administration
β-Adrenergic receptor agonist
Bioavailability
In vitro
Pyridine derivatives
β-Adrenergic receptor
In vivo
Vertebrata
Mammalia
Structure activity relation
Animal
Carboxamide
Pharmacokinetics
Chemical synthesis
Dog
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ISSN:0960-894X
1464-3405
DOI:10.1016/S0960-894X(00)00390-5