ChemInform Abstract: Synthesis of Aminomethylated 4-Fluoropiperidines and 3-Fluoropyrrolidines

Key step of the title synthesis is the regioselective bromofluorination of methylenepiperidines and ‐pyrrolidines (I) with NBS and Et3N·3HF.

Saved in:
Bibliographic Details
Published inChemInform Vol. 41; no. 43; p. no
Main Authors Verniest, Guido, Piron, Karel, Van Hende, Eva, Thuring, Jan Willem, Macdonald, Gregor, Deroose, Frederik, De Kimpe, Norbert
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 26.10.2010
WILEY‐VCH Verlag
Subjects
halogenation
pyridine derivatives
pyrrole derivatives
Online AccessGet full text

Cover

More Information
Summary:Key step of the title synthesis is the regioselective bromofluorination of methylenepiperidines and ‐pyrrolidines (I) with NBS and Et3N·3HF.
Bibliography:ArticleID:CHIN201043148
istex:D9D4E4A05387CC7F32CFA27B1F8EA4B7FE329F63
ark:/67375/WNG-PW4B864L-5
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201043148