ChemInform Abstract: Cascade Assembly of N,N′-Dialkylbarbituric Acids and Aldehydes: A Simple and Efficient One-Pot Approach to the Substituted 1,5-Dihydro-2H,2′H-spiro(furo [2,3-d]pyrimidine-6,5′-pyrimidine)2,2′,4,4′,6′(1′H,3H,3′H)-pentone Framework

• Published in: ChemInform Vol. 42; no. 13; p. no
• Main Authors: Elinson, Michail N., Vereshchagin, Anatolii N., Stepanov, Nikita O., Belyakov, Pavel A., Nikishin, Gennady I.
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 29.03.2011; WILEY‐VCH Verlag
• Subjects: barbituric acid derivatives; fused pyrimidine derivatives; spirocyclic compounds
• ISSN: 0931-7597; 1522-2667
• DOI: 10.1002/chin.201113160

Reaction of barbituric acid (I) with aromatic aldehydes is investigated in the presence of bromine under 2 different sets of reaction conditions.