Method development and Validation of UV Spectrophotometric estimation of Remogliflozin Etabonate in bulk and its tablet dosage form

A simple, precise and sensitive UV spectrophotometric method has been developed for the estimation of Remogliflozin etabonate in bulk and pharmaceutical dosage Form. Remogliflozin etabonate shows Maximum Absorbance at 229nm. Beer’s law was obeyed in range of 2-10µg/ml. The correlation coefficient wa...

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Bibliographic Details
Published inResearch journal of pharmacy and technology Vol. 14; no. 4; pp. 2042 - 2044
Main Authors Vidhi, Dave, Patel, Paresh
Format Journal Article
LanguageEnglish
Published Raipur A&V Publications 29.04.2021
Subjects
Accuracy
Calibration
Diabetes
Drug dosages
Pharmaceuticals
Pharmacy
Standard deviation
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Summary:A simple, precise and sensitive UV spectrophotometric method has been developed for the estimation of Remogliflozin etabonate in bulk and pharmaceutical dosage Form. Remogliflozin etabonate shows Maximum Absorbance at 229nm. Beer’s law was obeyed in range of 2-10µg/ml. The correlation coefficient was found to be 0.9990. The result of interday and intraday precision shows standard deviation ranging from 0.050% - 0.254% and 0.058% - 0.258% for three concentration and three replicates. The Percentage recovery was found to be in the range of 98.94% - 99.86%. The LOD and LOQ were found to be 0.037µg/ml and 0.113µg/ml respectively. The purposed method was novel and successfully applied for the determination of Remogliflozin Etabonate in Tablet Dosage Form. The method was successfully validated according to ICH guidelines.
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ISSN:0974-3618
0974-360X
0974-306X
DOI:10.52711/0974-360X.2021.00362