Application of Thealoz® duo eye drops confers novel protective effects on the ocular surface of dry eye patients

• Published in: Acta ophthalmologica (Oxford, England) Vol. 100; no. S275
• Main Authors: Perumal, Natarajan, Jeong, Eunjin, Runde, Sarah, Manicam, Caroline, Pfeiffer, Norbert, Grus, Franz
• Format: Journal Article
• Language: English
• Published: Malden Wiley Subscription Services, Inc 01.12.2022
• Subjects: Apoptosis; Bioinformatics; Eye; Hyaluronic acid; Inflammation; Mass spectroscopy; Metabolic pathways; Proteomes; Proteomics; Trehalose

Purpose: The protective effect of Thealoz® Duo eye drops was investigated in patients with dry eye syndrome (DES) by clinical examination. Subsequently, the tear proteome alterations were characterized employing the mass spectrometry‐based proteomics platform. Methods: Fifty‐eight subjects underwent...