Non-Keratinizing Squamous Cell Carcinoma from the Nasal Cavity Mimicking Palatal Salivary Gland Tumor: Case Report

Non-keratinizing squamous cell carcinoma (NKSCC) is a rare malignancy of the nose and paranasal sinuses which is characterized by a unique anastomosing ribbon-like growth pattern with absent of limited maturation and keratinization. NKSCC accounts for 10-27% of sinonasal squamous cell carcinomas and...

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Published inThe Korean Journal of Oral and Maxillofacial Pathology Vol. 45; no. 4; pp. 139 - 144
Main Authors Lee, Hwangyu, Han, Dawool, Kim, Hyounmin, Kim, Dongwook
Format Journal Article
LanguageEnglish
Published 대한구강악안면병리학회 30.08.2021
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Summary:Non-keratinizing squamous cell carcinoma (NKSCC) is a rare malignancy of the nose and paranasal sinuses which is characterized by a unique anastomosing ribbon-like growth pattern with absent of limited maturation and keratinization. NKSCC accounts for 10-27% of sinonasal squamous cell carcinomas and some of the NKSCCs are reported to be associated with high risk-HPV infection. Advanced lesion can involve the oral cavity with oral symptoms of palatal bulging, surface ulceration mimicking salivary gland tumors. Herein, we report a case of NKSCC of a 46-year old male, which clinically presented as a bulging mass on the mid palate and mimicked a palatal salivary gland tumor. We reviewed the clinical and histopathological considerations required for differential diagnosis of sinonasal carcinoma involving the oral cavity. KCI Citation Count: 0
ISSN:1225-1577
2384-0900
DOI:10.17779/KAOMP.2021.45.4.005