Coalescence of liquid or gel-like DNA-encapsulating microdroplets
Liquid-liquid phase separation plays a prominent role in the physics of life, providing the cells with various membrane-less compartments. These structures exhibit a range of material properties that, in many cases, change over time. Inspired by this, we investigate here an aqueous two-phase system...
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| Published in | The Journal of chemical physics Vol. 161; no. 13 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
United States
07.10.2024
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| Online Access | Get more information |
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| Summary: | Liquid-liquid phase separation plays a prominent role in the physics of life, providing the cells with various membrane-less compartments. These structures exhibit a range of material properties that, in many cases, change over time. Inspired by this, we investigate here an aqueous two-phase system formed by mixing polyethylene glycol with dextran. We modulate the material properties of the resulting dextran droplets by adding DNA that readily enters the droplets. We find a non-monotonic dependence of the physical properties of the droplets under the imposed ionic conditions. |
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| ISSN: | 1089-7690 |
| DOI: | 10.1063/5.0223951 |