Benzodiazepine actions mediated by specific γ-aminobutyric acidA receptor subtypes

GABAA (gamma-aminobutyric acidA) receptors are molecular sub strates for the regulation of vigilance, anxiety, muscle tension, epileptogenic activity and memory functions, which is evident from the spectrum of actions elicited by clinically effective drugs acting at their modulatory benzodiazepine-b...

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Bibliographic Details
Published inNature (London) Vol. 401; no. 6755; pp. 796 - 800
Main Authors Rudolph, Uwe, Crestani, Florence, Benke, Dietmar, Brunig, Ina
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group 21.10.1999
Subjects
Drug therapy
Ethanol
Insomnia
Laboratory animals
Side effects
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Summary:GABAA (gamma-aminobutyric acidA) receptors are molecular sub strates for the regulation of vigilance, anxiety, muscle tension, epileptogenic activity and memory functions, which is evident from the spectrum of actions elicited by clinically effective drugs acting at their modulatory benzodiazepine-binding site.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0028-0836
1476-4687
DOI:10.1038/44579