Peptide Synthesis in Ionic Liquids (PEPSIL): All You Need is in the Toolbox

This personal account describes our studies regarding peptide synthesis in ionic liquids (PEPSIL). In addition, we summarize our experiments in which the use of ionic liquids gives simple and promising access to unnatural amino acids in an enantiomerically enriched form. Extension of PEPSIL method t...

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Bibliographic Details
Published inFrench-Ukrainian journal of chemistry Vol. 4; no. 1; pp. 3 - 13
Main Authors Jebri, Khouloud, Galya, Nicolas, Zgonnik, Viacheslav, Mazières, Marie-Rose, Génisson, Yves, Guillen, Frédéric, Ben Ayed, Taïcir, Baltas, Michel, Plaquevent, Jean-Christophe
Format Journal Article
LanguageEnglish
Published 2016
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Summary:This personal account describes our studies regarding peptide synthesis in ionic liquids (PEPSIL). In addition, we summarize our experiments in which the use of ionic liquids gives simple and promising access to unnatural amino acids in an enantiomerically enriched form. Extension of PEPSIL method to complex structures such as cyclopeptides is also discussed. Some of these cyclopeptides are the direct precursors of bioactive and pharmaceutical compounds.
ISSN:2312-3222
2312-3222
DOI:10.17721/fujcV4I1P3-13