5.52 Toddler Cortisol Profiles Predicts Early Childhood Anxiety in a Prenatally Stressed Cohort: The QF2011 Queensland Flood Study

Researchers have linked prenatal maternal stress (PNMS) to childhood anxiety symptoms. It is thought that disturbances to environmental factors, including PNMS exposure during pregnancy, influence fetal biological systems, including the hypothalamo-pituitary-adrenal (HPA)-axis, thus enhancing suscep...

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Bibliographic Details
Published inJournal of the American Academy of Child and Adolescent Psychiatry Vol. 57; no. 10; p. S243
Main Authors Mclean, Mia A., Simcock, Gabrielle, Elgbeili, Guillaume, Cobham, Vanessa E., Kildea, Sue, King, Suzanne
Format Journal Article
LanguageEnglish
Published Baltimore Elsevier Inc 01.10.2018
Elsevier BV
Subjects
Anxiety
Child & adolescent psychiatry
Childhood
Children
Childrens health
Cortisol
Emotional disturbances
Endocrine therapy
Environmental aspects
Environmental factors
Fetuses
Heritability
Hypothalamic-pituitary-adrenal axis
Maternal stress
Mental health
Pituitary
Pregnancy
Pregnancy complications
Prenatal care
Prenatal experience
Stress
Susceptibility
Toddlers
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Summary:Researchers have linked prenatal maternal stress (PNMS) to childhood anxiety symptoms. It is thought that disturbances to environmental factors, including PNMS exposure during pregnancy, influence fetal biological systems, including the hypothalamo-pituitary-adrenal (HPA)-axis, thus enhancing susceptibility to emotional problems, including anxiety. Yet understanding causal biological mechanisms are hindered because of associations that are probably confounded by postnatal and/or shared mother-child heritability effects.
ISSN:0890-8567
1527-5418
DOI:10.1016/j.jaac.2018.09.345