In Vitro comparison of the performance of salmeterol/fluticasone propionate HFA Metered Dose Inhaler (MDI) with and without MDI counter

• Published in: Journal of allergy and clinical immunology Vol. 115; no. 2; p. S149
• Main Authors: West, J.J., O'Brien, O., Ellis, J.C., O'Brien, C.A.
• Format: Journal Article
• Language: English
• Published: St. Louis Mosby, Inc 01.02.2005; Elsevier Limited
• Subjects: Allergies
• ISSN: 0091-6749; 1097-6825
• DOI: 10.1016/j.jaci.2004.12.608

For both the salmeterol (S) and fluticasone propionate (FP) components, product tested with/without MDI counter gave similar results for mean content per actuation (n=10 cans) and mean FPM (n=3 cans) for each of the product strengths: SFC 25 μg/50 μg: mean content per actuation 22/22μg (S), 47/47μg (FP); mean FPM 11/11μg (S), 22/24μg(FP).