The Pathogenesis of Acute on Chronic Hepatitis B Liver Failure

Acute-on-chronic liver failure is a characteristic clinical liver syndrome, which should be differentiated from acute liver failure, acute decompensated liver cirrhosis and chronic liver failure. The pathogenesis of ACLF is not fully understood yet. Viral factors and immune injury have been reported...

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Bibliographic Details
Published inInfection international Vol. 3; no. 1; pp. 31 - 34
Main Authors Chi, Zhao-chun, Dong, Quan-jiang, Geng, Chang-xin
Format Journal Article
LanguageEnglish
Published De Gruyter Open 01.03.2014
Subjects
Acute on chronic hepatitis B liver failure
Cytokine
Immune injury
Pathogenesis
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Summary:Acute-on-chronic liver failure is a characteristic clinical liver syndrome, which should be differentiated from acute liver failure, acute decompensated liver cirrhosis and chronic liver failure. The pathogenesis of ACLF is not fully understood yet. Viral factors and immune injury have been reported to be the two major pathogenesis. This paper reviewed the researches on the pathogenesis of acute on chronic hepatitis B liver failure in recent years, to provide theoretical basis for prompt and accurate diagnosis and treatment of this syndrome. This would benefit for the prognosis and raise the survival rate of patients.
ISSN:2544-0349
2544-0349
DOI:10.1515/ii-2017-0070