Further secondary metabolites from Pimpinella kotschyana

• Published in: Planta Medica
• Main Authors: Demirezer, LÖ, Kuruüzüm-Uz, A, Guvenalp, Z, Simon, A, Patócs, T
• Format: Conference Proceeding
• Language: English
• Published: 19.07.2012
• ISSN: 0032-0943; 1439-0221
• DOI: 10.1055/s-0032-1321093

Pimpinella (Apiaceae) is represented in Turkey by 23 species (5 endemic), 2 subspecies, and 2 varieties. Pimpinella anisum L. is a medicinal herb known for its expectorant, antispasmodic, carminative, and diuretic properties properties and it is an important agricultural crop in Turkey. Pimpinella species have used as carminative, expectorant, sedative, antidepressant, antiseptic, insecticidal, antiviral, antispasmodic, nematocidal, mutagenic, analgesic, antifungal and antibacterial agent. It was found that the existence of terpenoids, lipids, alkaloids, coumarins, flavonoids and phenylpropanoids in Pimpinella species. In our earlier studies of isolated compounds from Pimpinella kotschyana, we reported 2 new and 4 known flavonol glycosides. In our further research on this plant, n -BuOH phase prepared from methanol extract was fractionated on a silica gel column. The subfractions were rechromatographed over silica gel and Sephadex LH-20 to give two new acylated flavonol glycosides ( Quercetin 3- O - α -L-(3''- trans -coumaroil) rhamnopyranoside and Quercetin 3- O - α -L-(2'',3''-di- trans -coumaroil) rhamnopyranoside), a new triterpene glycoside (saikogenin F 3- O {β-D-glucopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→4)-β-D-glucopyranosyl-(1→3)]-β-D-fucopyranoside}), one erithritol derivative (2-C-methylerithritol) and one sterol (α-spinasterol-β-D-glucopyranoside). The structures of isolated compounds were determined by 1D and 2D NMR analysis.This is the first report describing of these isolated compounds from the aerial parts of Pimpinella kotschyana.