The expression and activation of the AIM2 inflammasome correlates with inflammation and disease severity in patients with acute pancreatitis
Results: Our results show that PBMCs from patients with acute pancreatitis have elevated expression of several components of the inflammasome complex, including the inflammasome-forming receptor absent in melanoma 2 (AIM2), early during the onset of the disease. [...]AIM2 expression was further incr...
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Published in | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] Vol. 17; no. 5; pp. S5 - S6 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Philadelphia
Elsevier B.V
01.09.2017
Elsevier Limited |
Subjects | |
Online Access | Get full text |
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Summary: | Results: Our results show that PBMCs from patients with acute pancreatitis have elevated expression of several components of the inflammasome complex, including the inflammasome-forming receptor absent in melanoma 2 (AIM2), early during the onset of the disease. [...]AIM2 expression was further increased in those patients that developed transient or persistent organ failure (moderate or severe acute pancreatitis). |
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ISSN: | 1424-3903 1424-3911 |
DOI: | 10.1016/j.pan.2017.08.027 |