Role of ultrasound guided injection of platelet rich plasma (PRP) in knee osteoarthritis patients

• Published in: QJM : An International Journal of Medicine Vol. 114; no. Supplement_1
• Main Authors: Mohamed, Ahmed Emad Mahdy, Hassan, Mohamed Sobhy, AbdelMotelib, Mohamed Gamal Eldin
• Format: Journal Article
• Language: English
• Published: Oxford University Press 01.10.2021
• Subjects: Knee; pain; osteoarthritis; Ultrasonography; PRP
• ISSN: 1460-2725; 1460-2393
• DOI: 10.1093/qjmed/hcab106.002

Abstract Background Multiple promising researches were done regarding using platelet rich plasma (PRP) injection aiming at establishing new minimally invasive treatment option for knee OA and avoiding surgical procedures hazards which could be an option in advanced cases. Thus, our study will be directed towards ultrasound guided injecting of PRP trying to confirm the efficacy of the procedure as a therapeutic option. Objective The study aims to assess of the role of ultrasound guided PRP injection in cases of knee osteoarthritis and follow up of the symptoms outcome. Methods and material Twenty patients with different knee osteoarthritis grades were injected with PRP under ultrasound guidance and the symptoms outcome were followed up by using visual analogue scale (VAS), WOMAC osteoarthritis index, OXFORD knee score, LYSHOLM knee scoring scale at periods of , and weeks post procedure. Results A total of patients were included with the age ranging from - years old, the mean was . years old (SD ± . ). Among them patients ( ) were females and patients ( ) were males. There was statistically significant difference between the different knee pain scoring scales , and weeks after the procedure compared to before injection, where according to VAS score the mean score was . . pre procedure and became . . , . . and . . after , and weeks respectively with mean reduction ratio of . % after months. The extent of the difference over the periods through WOMAC in knee osteoarthritis patients was . . ,. . and . . after , and weeks respectively, compared to . . before the procedure with a mean reduction ratio of . % after months. While according to OXFORD knee score, the patient’s scores were . . before the procedure Vs . . , . . and . . at , and weeks after injection with symptoms mean reduction ratio of . %. According to LYSHOLM knee scoring scale, the mean score was . . pre procedure and became . . , . . and . . after , and weeks respectively with months mean reduction ratio of . %. Conclusion PRP injection in symptomatic knee osteoarthritis patients cause statistically significant improvement of the symptoms. Fig ( ): Line shows the extent of the difference over the periods through WOMAC in knee osteoarthritis patients.